COQ4 Antibody (PACO42726)
- SKU:
- PACO42726
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | COQ4 Antibody (PACO42726) |
| Antibody SKU: | PACO42726 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial protein (31-265AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human liver tissue using PACO42726 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human spleen tissue using PACO42726 at dilution of 1:100. |
| Background: | Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides. |
| Synonyms: | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial (Coenzyme Q biosynthesis protein 4 homolog), COQ4 |
| UniProt Protein Function: | COQ4: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides. Belongs to the COQ4 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: MitochondrialChromosomal Location of Human Ortholog: 9q34.11Cellular Component: mitochondrionBiological Process: ubiquinone biosynthetic processDisease: Coenzyme Q10 Deficiency, Primary, 7 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a component of the coenzyme Q biosynthesis pathway. Coenzyme Q, an essential component of the electron transport chain, shuttles electrons between complexes I or II to complex III of the mitochondrial transport chain. This protein appears to play a structural role in stabilizing a complex that contains most of the coenzyme Q biosynthesis enzymes. Mutations in this gene are associated with mitochondrial disorders linked to coenzyme Q deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] |
| UniProt Code: | Q9Y3A0 |
| NCBI GenInfo Identifier: | 40225458 |
| NCBI Gene ID: | 51117 |
| NCBI Accession: | BC011895 |
| UniProt Secondary Accession: | Q9Y3A0,Q5T4B8, Q96EW4, A8WBK8, B2R958 |
| UniProt Related Accession: | Q9Y3A0 |
| Molecular Weight: | 27,043 Da |
| NCBI Full Name: | Homo sapiens coenzyme Q4 homolog (S. cerevisiae), mRNA |
| NCBI Synonym Full Names: | coenzyme Q4 |
| NCBI Official Symbol: | COQ4 |
| NCBI Official Synonym Symbols: | CGI-92; COQ10D7 |
| NCBI Protein Information: | ubiquinone biosynthesis protein COQ4 homolog, mitochondrial |
| UniProt Protein Name: | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial |
| UniProt Synonym Protein Names: | Coenzyme Q biosynthesis protein 4 homolog |
| Protein Family: | Ubiquinone biosynthesis protein |
| UniProt Gene Name: | COQ4 |
| UniProt Entry Name: | COQ4_HUMAN |
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