COP1 Polyclonal Antibody
- SKU:
- CAB22106
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | COP1 Polyclonal Antibody |
| Product Code: | CAB22106 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | 293T |
| Cellular Location: | Cytoplasm, Nucleus speckle |
Enables ubiquitin protein ligase activity. Involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process; proteasome-mediated ubiquitin-dependent protein catabolic process; and response to ionizing radiation. Part of Cul4A-RING E3 ubiquitin ligase complex.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 582-731 of human COP1 (NP_071902.2). |
| Sequence: | YYDLR NTKQP IMVFK GHRKA VSYAK FVSGE EIVSA STDSQ LKLWN VGKPY CLRSF KGHIN EKNFV GLASN GDYIA CGSEN NSLYL YYKGL SKTLL TFKFD TVKSV LDKDR KEDDT NEFVS AVCWR ALPDG ESNVL IAANS QGTIK VLELV |
| Synonyms: | FAP78, RFWD2, CFAP78, RNF200 |
| Calculated MW: | 80kDa |
| Observed MW: | 102kDa |
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