Connexin 43 Monoclonal Antibody (CAB23120)
- SKU:
- CAB23120
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Connexin 43 Monoclonal Antibody |
| Product Code: | CAB23120 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC58819 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | A549, Mouse brain, Rat brain, U-251 MG |
| Cellular Location: | Cell junction, Cell membrane, Endoplasmic reticulum, Multi-pass membrane protein, Gap junction |
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300-382 of human Connexin 43 (NP_000156.1). |
| Sequence: | NYNKQ ASEQN WANYS AEQNR MGQAG STISN SHAQP FDFPD DNQNS KKLAA GHELQ PLAIV DQRPS SRASS RASSR PRPDD LEI |
| Synonyms: | HSS, CMDR, CX43, EKVP, GJAL, ODDD, AVSD3, EKVP3, HLHS1, PPKCA |
| Calculated MW: | 43kDa |
| Observed MW: | 43kDa |
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