Complement factor D Polyclonal Antibody
- SKU:
- CAB22110
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Complement factor D Polyclonal Antibody |
| Product Code: | CAB22110 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | THP-1, U-87MG(negative) |
| Cellular Location: | extracellular exosome, extracellular region |
This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.
| Immunogen: | Recombinant protein of human Complement factor D |
| Sequence: | Email for sequence |
| Synonyms: | DF, ADN, PFD, ADIPSIN |
| Calculated MW: | 27kDa |
| Observed MW: | 27kDa |
Related Products
Complement factor D Monoclonal Antibody
OverviewProduct Name:Complement factor D Monoclonal AntibodyProduct Code:CAB23006Reactivity:HumanApplications:Western blotting
Human Complement factor D / Factor D ELISA Kit
Human Complement factor D / Factor D ELISA KitFactor D is a protein that regulates the production of C3 and C4 complement proteins. Factor D deficiency can cause hemolytic anemia and immune...
Complement factor B (CFB) Monoclonal Antibody
OverviewProduct Name:Complement factor B (CFB) Monoclonal AntibodyProduct Code:CAB21793Reactivity:Human, MouseApplications:Wester
Anti-Complement factor H Antibody (CAB8798)
OverviewProduct Name:Complement factor H Rabbit mAbProduct Code:CAB8798Size:20uL, 50uL, 100uLSynonyms:AHUS1, AMBP1, ARMD4, ARMS1, CFHL3,
