Description
Antibody Name: | COL5A3 Antibody (PACO23314) |
Antibody SKU: | PACO23314 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:50-1:100, IF:1:100-1:500 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from internal of human Collagen V alpha 3. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Collagen V alpha 3 antibody. |
![]() | Immunofluorescence analysis of HeLa cells, using Collagen V alpha 3 antibody. |
Background: | Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. |
Synonyms: | CO5A3; collagen alpha 3; |
UniProt Protein Function: | Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are thought to be responsible for the symptoms of a subset of patients with Ehlers-Danlos syndrome type III. Messages of several sizes can be detected in northern blots but sequence information cannot confirm the identity of the shorter messages. [provided by RefSeq, Jul 2008] |
UniProt Code: | P25940 |
NCBI GenInfo Identifier: | 110735435 |
NCBI Gene ID: | 50509 |
NCBI Accession: | NP_056534.2 |
UniProt Secondary Accession: | P25940,Q9NZQ6 |
UniProt Related Accession: | P25940 |
Molecular Weight: | 172,121 Da |
NCBI Full Name: | collagen alpha-3(V) chain preproprotein |
NCBI Synonym Full Names: | collagen type V alpha 3 chain |
NCBI Official Symbol: | COL5A3 |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | collagen alpha-3(V) chain |
UniProt Protein Name: | Collagen alpha-3(V) chain |
UniProt Synonym Protein Names: | |
Protein Family: | |
UniProt Gene Name: | COL5A3 |
UniProt Entry Name: |
Antibodies |
COL5A3 Antibody (PACO06368) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |