Description
| Product Name: | COL11A1 Monoclonal Antibody |
| Product Code: | CAB24604 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC63678 |
| Reactivity: | Human |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:1000-1:5000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: 59% PBS with 0.01% Sodium azide, 0.05% BSA, 40% Glycerol, PH 7.2 |
| Positive Samples: | A-204, U-2 OS(Low expression control) |
| Cellular Location: | Secreted, extracellular matrix, extracellular space |
This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single-nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants have been identified for this gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 301-400 of human COL11A1 mAb (NP_001845.3). |
| Sequence: | NIVDD FQEYN YGTME SYQTE APRHV SGTNE PNPVE EIFTE EYLTG EDYDS QRKNS EDTLY ENKEI DGRDS DLLVD GDLGE YDFYE YKEYE DKPTS PPNEE |
| Synonyms: | STL2, COLL6, CO11A1, DFNA37 |
| Calculated MW: | 167kDa/176kDa/181kDa/182kDa |
| Observed MW: | 280kDa |