Cardiovascular Recombinant Proteins
Coagulation Factor X/F10 Recombinant Protein (RPES3430)
- SKU:
- RPES3430
Description
Coagulation Factor X/F10 Recombinant Protein
F10, also known as Coagulation factor X, belongs to the peptidase S1 family that is synthesized as a 488 amino acid (aa) with a signal peptide and a pro region (residues 1-40). Both the intrinsic and extrinsic pathways activate Factor X to Xa, which consists of light (residues 41-179) and heavy (residues 235-488) chains linked by a disulfide bond. Coagulation factor X is initially synthesized in the liver. The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds. Forms a heterodimer with SERPINA5. F10 is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.
| Product Name: | Coagulation Factor X/F10 Recombinant Protein (RPES3430) |
| Product Code: | RPES3430 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Coagulation factor 10,coagulation factor X,FX,FXA |
| Accession: | P00742 |
| Sequence: | Asp22-Phe96 |
| Fusion tag: | C-Fc |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Coagulation Factor X is produced by our Mammalian expression system and the target gene encoding Asn32-Lys488 is expressed with a Fc tag at the C-terminus. |
| Purity: | > 85% as determined by reducing SDS-PAGE. |
| Mol Mass: | 78.2 kDa |
| AP Mol Mass: | 94 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM MES,150mM NaCl,0.2mM CaCl2,pH5.5. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Human |
Research Area: |
Cardiovascular |
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Cardiovascular Recombinant Proteins