Description
Antibody Name: | COA6 Antibody (PACO36110) |
Antibody SKU: | PACO36110 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Cytochrome c oxidase assembly factor 6 homolog protein (1-125AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO36110 at dilution of 1:100. |
Background: | Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV assembly. Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis. May also be required for efficient formation of respiratory supercomplexes comprised of complexes III and IV. |
Synonyms: | Cytochrome c oxidase assembly factor 6 homolog, COA6, C1orf31 |
UniProt Protein Function: | |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of the cytochrome c oxidase subunit 6B family. The encoded protein associates with cytochrome c oxidase may act has an cytochrome c oxidase mitochondrial respiratory complex VI assembly factor. Mutations in this gene may be associated with fatal infantile cardiomyopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014] |
UniProt Code: | Q5JTJ3 |
NCBI GenInfo Identifier: | 61175258 |
NCBI Gene ID: | 388753 |
NCBI Accession: | NP_001013003 |
UniProt Secondary Accession: | Q5JTJ3 |
UniProt Related Accession: | Q5JTJ3 |
Molecular Weight: | 13kDa |
NCBI Full Name: | cytochrome c oxidase assembly factor 6 homolog isoform 1 |
NCBI Synonym Full Names: | cytochrome c oxidase assembly factor 6 |
NCBI Official Symbol: | COA6 |
NCBI Official Synonym Symbols: | C1orf31; CEMCOX4 |
NCBI Protein Information: | cytochrome c oxidase assembly factor 6 homolog |
UniProt Protein Name: | Cytochrome c oxidase assembly factor 6 homolog |
UniProt Synonym Protein Names: | |
Protein Family: | Cytochrome c oxidase assembly factor |
UniProt Gene Name: | COA6 |
UniProt Entry Name: | COA6_HUMAN |