Name: COA1 Antibody (PACO25404)
SKU: PACO25404
Availability: OutOfStock

Antibody Name:	COA1 Antibody (PACO25404)
Antibody SKU:	PACO25404
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, IHC, IF
Recommended Dilutions:	ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200
Species Reactivity:	Human
Immunogen:	Recombinant Human Cytochrome c oxidase assembly factor 1 homolog protein (38-146AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Immunohistochemistry of paraffin-embedded human kidney tissue using PACO25404 at dilution of 1:100.
	Immunofluorescent analysis of U251 cells using PACO25404 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
	Immunohistochemistry of paraffin-embedded human breast cancer using PACO25404 at dilution of 1:100.

Background:	Component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex that regulates COX assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for assembly of mitochondrial respiratory chain complex I and complex IV.
Synonyms:	Cytochrome c oxidase assembly factor 1 homolog (Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 15 kDa), COA1, C7orf44 MITRAC15

UniProt Protein Function:	COA1: Belongs to the COA1 family.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 7p13Cellular Component: cytoplasm; integral to mitochondrial inner membrane; mitochondrionMolecular Function: RNA binding; structural constituent of ribosomeBiological Process: mitochondrial respiratory chain complex I assembly; mitochondrial respiratory chain complex IV assembly; translation
UniProt Protein Details:
NCBI Summary:
UniProt Code:	Q9GZY4
NCBI GenInfo Identifier:	90855771
NCBI Gene ID:	55744
NCBI Accession:	NP_060694.2
UniProt Secondary Accession:	Q9GZY4,Q9HAB7, Q9NVD2, A6NJU8, A8KAH8
UniProt Related Accession:	Q9GZY4
Molecular Weight:	16,694 Da
NCBI Full Name:	cytochrome c oxidase assembly factor 1 homolog
NCBI Synonym Full Names:	cytochrome c oxidase assembly factor 1 homolog
NCBI Official Symbol:	COA1
NCBI Official Synonym Symbols:	C7orf44; MITRAC15
NCBI Protein Information:	cytochrome c oxidase assembly factor 1 homolog
UniProt Protein Name:	Cytochrome c oxidase assembly factor 1 homolog
UniProt Synonym Protein Names:	Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 15 kDa
Protein Family:	Cytochrome c oxidase assembly factor
UniProt Gene Name:	COA1
UniProt Entry Name:	COA1_HUMAN