Description
Antibody Name: | CNOT4 Antibody (PACO08494) |
Antibody SKU: | PACO08494 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human CNOT4 |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | CCR4-NOT transcription complex, subunit 4;CNOT4;CLONE243;NOT4;NOT4H ; |
UniProt Protein Function: | CNOT4: Has E3 ubiquitin ligase activity. The CCR4-NOT complex functions as general transcription regulation complex. 8 isoforms of the human protein are produced by alternative splicing.Protein type: Ubiquitin conjugating system; EC 6.3.2.19; EC 6.3.2.-; Ligase; Ubiquitin ligaseChromosomal Location of Human Ortholog: 7q33Cellular Component: CCR4-NOT complex; cytosolMolecular Function: protein binding; ubiquitin-protein ligase activityBiological Process: DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; poly(A) tail shortening; protein autoubiquitination |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene is a subunit of the CCR4-NOT complex, a global transcriptional regulator. The encoded protein interacts with CNOT1 and has E3 ubiquitin ligase activity. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010] |
UniProt Code: | O95628 |
NCBI GenInfo Identifier: | 115502372 |
NCBI Gene ID: | 4850 |
NCBI Accession: | O95628.3 |
UniProt Secondary Accession: | O95628,O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6 B7Z6I4, E7ET38, F8VQP3 |
UniProt Related Accession: | O95628 |
Molecular Weight: | 78,257 Da |
NCBI Full Name: | CCR4-NOT transcription complex subunit 4 |
NCBI Synonym Full Names: | CCR4-NOT transcription complex subunit 4 |
NCBI Official Symbol: | CNOT4 |
NCBI Official Synonym Symbols: | NOT4; NOT4H; CLONE243 |
NCBI Protein Information: | CCR4-NOT transcription complex subunit 4 |
UniProt Protein Name: | CCR4-NOT transcription complex subunit 4 |
UniProt Synonym Protein Names: | CCR4-associated factor 4; E3 ubiquitin-protein ligase CNOT4; Potential transcriptional repressor NOT4Hp |
Protein Family: | CCR4-NOT transcription complex |
UniProt Gene Name: | CNOT4 |
UniProt Entry Name: | CNOT4_HUMAN |