Name: CNKSR1 Antibody (PACO21922)
SKU: PACO21922
Availability: OutOfStock

Antibody Name:	CNKSR1 Antibody (PACO21922)
Antibody SKU:	PACO21922
Size:	100ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:	Human, Mouse, Rat
Immunogen:	Synthesized peptide derived from internal of human CNKR1.

Form:	Liquid
Storage Buffer:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Western blot analysis of extracts from COLO cells, using CNKR1 antibody.

Background:	May function as an adapter protein or regulator of Ras signaling pathways. The MGC Project Team, Genome Res. 14:2121-2127(2004).
Synonyms:	Connector enhancer of KSR1; hCNK1; Connector enhancer of KSR-like; CNK homolog protein 1;

UniProt Protein Function:	CNK1: a RAF-binding multidomain protein required for RAS signaling. Contains several protein-protein interaction domains. Its PH domain interacts with Rho in a GTP-dependent manner. Associates with Rhophilin and RalGDS, Rho and Ras effector molecules. Two alternatively spliced isoforms have been described.Protein type: G protein regulator, misc.; Adaptor/scaffoldChromosomal Location of Human Ortholog: 1p36.11Cellular Component: plasma membrane; cell cortex; intercellular junctionMolecular Function: protein binding, bridgingBiological Process: Ras protein signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway; Rho protein signal transduction
UniProt Protein Details:
NCBI Summary:	This gene encodes a protein containing several motifs involved in protein-protein interaction, including PDZ, PH (Pleckstrin homology), and SAM (sterile alpha motif) domains. The encoded protein acts as a scaffold component for receptor tyrosine kinase signaling and may mediate crosstalk between different signaling pathways. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
UniProt Code:	Q969H4
NCBI GenInfo Identifier:	50400606
NCBI Gene ID:	10256
NCBI Accession:	Q969H4.1
UniProt Secondary Accession:	Q969H4,O95381, B1AMW9
UniProt Related Accession:	Q969H4
Molecular Weight:	67 kDa
NCBI Full Name:	Connector enhancer of kinase suppressor of ras 1
NCBI Synonym Full Names:	connector enhancer of kinase suppressor of Ras 1
NCBI Official Symbol:	CNKSR1
NCBI Official Synonym Symbols:	CNK; CNK1
NCBI Protein Information:	connector enhancer of kinase suppressor of ras 1; CNK homolog protein 1; connector enhancer of KSR 1
UniProt Protein Name:	Connector enhancer of kinase suppressor of ras 1
UniProt Synonym Protein Names:	CNK homolog protein 1; CNK1; hCNK1; Connector enhancer of KSR-like
Protein Family:	Connector enhancer of kinase suppressor of ras
UniProt Gene Name:	CNKSR1
UniProt Entry Name:	CNKR1_HUMAN

Antibodies	ELISA Kits
CNKSR1 Antibody (PACO02308)	Human CNKSR1 (Connector enhancer of kinase suppressor of ras 1) ELISA Kit (HUFI07962)
CNKSR1 Antibody (PACO08484)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)