CNKSR1 Antibody (PACO21922)
- SKU:
- PACO21922
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CNKSR1 Antibody (PACO21922) |
| Antibody SKU: | PACO21922 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from internal of human CNKR1. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from COLO cells, using CNKR1 antibody. |
| Background: | May function as an adapter protein or regulator of Ras signaling pathways. The MGC Project Team, Genome Res. 14:2121-2127(2004). |
| Synonyms: | Connector enhancer of KSR1; hCNK1; Connector enhancer of KSR-like; CNK homolog protein 1; |
| UniProt Protein Function: | CNK1: a RAF-binding multidomain protein required for RAS signaling. Contains several protein-protein interaction domains. Its PH domain interacts with Rho in a GTP-dependent manner. Associates with Rhophilin and RalGDS, Rho and Ras effector molecules. Two alternatively spliced isoforms have been described.Protein type: G protein regulator, misc.; Adaptor/scaffoldChromosomal Location of Human Ortholog: 1p36.11Cellular Component: plasma membrane; cell cortex; intercellular junctionMolecular Function: protein binding, bridgingBiological Process: Ras protein signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway; Rho protein signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein containing several motifs involved in protein-protein interaction, including PDZ, PH (Pleckstrin homology), and SAM (sterile alpha motif) domains. The encoded protein acts as a scaffold component for receptor tyrosine kinase signaling and may mediate crosstalk between different signaling pathways. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
| UniProt Code: | Q969H4 |
| NCBI GenInfo Identifier: | 50400606 |
| NCBI Gene ID: | 10256 |
| NCBI Accession: | Q969H4.1 |
| UniProt Secondary Accession: | Q969H4,O95381, B1AMW9 |
| UniProt Related Accession: | Q969H4 |
| Molecular Weight: | 67 kDa |
| NCBI Full Name: | Connector enhancer of kinase suppressor of ras 1 |
| NCBI Synonym Full Names: | connector enhancer of kinase suppressor of Ras 1 |
| NCBI Official Symbol: | CNKSR1 |
| NCBI Official Synonym Symbols: | CNK; CNK1 |
| NCBI Protein Information: | connector enhancer of kinase suppressor of ras 1; CNK homolog protein 1; connector enhancer of KSR 1 |
| UniProt Protein Name: | Connector enhancer of kinase suppressor of ras 1 |
| UniProt Synonym Protein Names: | CNK homolog protein 1; CNK1; hCNK1; Connector enhancer of KSR-like |
| Protein Family: | Connector enhancer of kinase suppressor of ras |
| UniProt Gene Name: | CNKSR1 |
| UniProt Entry Name: | CNKR1_HUMAN |
| Antibodies | ELISA Kits |
| CNKSR1 Antibody (PACO02308) | Human CNKSR1 (Connector enhancer of kinase suppressor of ras 1) ELISA Kit (HUFI07962) |
| CNKSR1 Antibody (PACO08484) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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