CMTR2 Antibody (PACO37750)
- SKU:
- PACO37750
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CMTR2 Antibody (PACO37750) |
| Antibody SKU: | PACO37750 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 protein (301-600AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human skin tissue using PACO37750 at dilution of 1:100. |
 | Immunofluorescent analysis of MCF-7 cells using PACO37750 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m(7)GpppRmpNm (cap2). Recognizes a guanosine cap on RNA independently of its N(7) methylation status. Display cap2 methylation on both cap0 and cap1. Displays a preference for cap1 RNAs. |
| Synonyms: | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296) (Cap methyltransferase 2) (Cap2 2'O-ribose methyltransferase 2) (HMTr2) (MTr2) (FtsJ methyltransferase domain-containing protein 1) (Protein adrift homolog), CMTR2, AFT FTSJD1 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8IYT2 |
| NCBI GenInfo Identifier: | 153791865 |
| NCBI Gene ID: | 55783 |
| NCBI Accession: | NP_060818 |
| UniProt Secondary Accession: | Q8IYT2 |
| UniProt Related Accession: | Q8IYT2 |
| Molecular Weight: | 88kDa |
| NCBI Full Name: | cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 |
| NCBI Synonym Full Names: | cap methyltransferase 2 |
| NCBI Official Symbol: | CMTR2 |
| NCBI Official Synonym Symbols: | AFT; MTr2; HMTr2; FTSJD1 |
| NCBI Protein Information: | cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 |
| UniProt Protein Name: | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 |
| UniProt Synonym Protein Names: | Cap methyltransferase 2; Cap2 2'O-ribose methyltransferase 2; HMTr2; MTr2; FtsJ methyltransferase domain-containing protein 1; Protein adrift homolog |
| Protein Family: | |
| UniProt Gene Name: | CMTR2 |
| UniProt Entry Name: | CMTR2_HUMAN |
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