Description
Antibody Name: | CLUAP1 Antibody (PACO38414) |
Antibody SKU: | PACO38414 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Clusterin-associated protein 1 protein (161-413AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO38414 at dilution of 1:100. |
Background: | Required for cilia biogenesis. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Key regulator of hedgehog signaling (By similarity). |
Synonyms: | Clusterin-associated protein 1 (Qilin), CLUAP1, KIAA0643 |
UniProt Protein Function: | CLUAP1: a nuclear protein commonly upregulated in colon cancers. It encodes a nuclear protein of 413 amino acids containing a coiled-coil domain. Associated with nuclear clusterin in a yeast two-hybrid system. Its expression gradually increases in the late S to G2/M phases of cell cycle and it returns to the basal level in the G0/G1 phases. RNAi suppression of this gene resulted in growth retardation in the transfected cells. Chromosomal Location of Human Ortholog: 16p13.3Cellular Component: centrosome; cilium; intracellular membrane-bound organelle; nucleoplasmMolecular Function: protein bindingBiological Process: cilium biogenesis |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene contains a single coiled-coil region. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012] |
UniProt Code: | Q96AJ1 |
NCBI GenInfo Identifier: | 108935970 |
NCBI Gene ID: | 23059 |
NCBI Accession: | Q96AJ1.4 |
UniProt Secondary Accession: | Q96AJ1,O75138, Q65ZA3, Q9H8R4, Q9H8T1 |
UniProt Related Accession: | Q96AJ1 |
Molecular Weight: | 29,093 Da |
NCBI Full Name: | Clusterin-associated protein 1 |
NCBI Synonym Full Names: | clusterin associated protein 1 |
NCBI Official Symbol: | CLUAP1 |
NCBI Official Synonym Symbols: | FAP22; IFT38; CFAP22 |
NCBI Protein Information: | clusterin-associated protein 1 |
UniProt Protein Name: | Clusterin-associated protein 1 |
UniProt Synonym Protein Names: | Qilin |
Protein Family: | Clusterin-associated protein |
UniProt Gene Name: | CLUAP1 |
UniProt Entry Name: | CLUA1_HUMAN |
Antibodies |
CLUAP1 Antibody (PACO08475) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |