Cleaved-MMP23A (Y79) Antibody (PACO00036)
- SKU:
- PACO00036
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Cleaved-MMP23A (Y79) Antibody |
| Antibody SKU: | PACO00036 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from the Internal region of human MMP-23. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | MMP23A; MMP21; MMP23B; MMP21; MMP22; Matrix metalloproteinase-23; MMP-23; Femalysin; MIFR-1; Matrix metalloproteinase-21; MMP-21; Matrix metalloproteinase-22; MMP-22 |
| UniProt Protein Function: | MMP23B: Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum. Belongs to the peptidase M10A family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; EC 3.4.24.-; Protease Chromosomal Location of Human Ortholog: 1p36.3 Cellular Component: proteinaceous extracellular matrix; endoplasmic reticulum membrane; integral to membrane; intracellular Molecular Function:zinc ion binding; metallopeptidase activity; metalloendopeptidase activity Biological Process: proteolysis; reproduction |
| NCBI Summary: | This gene (MMP23B) encodes a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated region of chromosome 1p36.3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene belongs to the more telomeric copy of the duplicated region. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O75900 |
| NCBI GenInfo Identifier: | 117949605 |
| NCBI Gene ID: | 8510 |
| NCBI Accession: | O75900.2 |
| UniProt Secondary Accession: | O75900,O75894, O75895, Q5QPQ8, Q76P96, Q7LDM6, Q7LDM7 Q9UBR9, Q9UJK8, A2AGN0, A2AGN1, |
| UniProt Related Accession: | O75900 |
| Molecular Weight: | 46,305 Da |
| NCBI Full Name: | Matrix metalloproteinase-23 |
| NCBI Synonym Full Names: | matrix metallopeptidase 23B |
| NCBI Official Symbol: | MMP23B |
| NCBI Official Synonym Symbols: | MIFR; MMP22; MIFR-1; MMP23A |
| NCBI Protein Information: | matrix metalloproteinase-23; MMP-21; MMP-22; MMP-23; femalysin; matrix metalloproteinase 22; matrix metalloproteinase 23B; matrix metalloproteinase in the female reproductive tract; matrix metalloproteinase-21; matrix metalloproteinase-22 |
| UniProt Protein Name: | Matrix metalloproteinase-23 |
| UniProt Synonym Protein Names: | Femalysin; MIFR-1; Matrix metalloproteinase-21; MMP-21; Matrix metalloproteinase-22; MMP-22 |
| UniProt Gene Name: | MMP23A |
| UniProt Entry Name: | MMP23_HUMAN |
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