Cleaved-GGT7 (T472) Antibody (PACO03860)
- SKU:
- PACO03860
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Cleaved-GGT7 (T472) Antibody |
| Antibody SKU: | PACO03860 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from the Internal region of human GGT4 HC. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | GGT7; GGTL3; GGTL5; Gamma-glutamyltransferase 7; GGT 7; Gamma-glutamyltransferase-like 3; Gamma-glutamyltransferase-like 5; Gamma-glutamyltranspeptidase 7; Glutathione hydrolase 7 |
| UniProt Protein Function: | GGTL3: Cleaves glutathione conjugates. Belongs to the gamma-glutamyltransferase family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Other Amino Acids Metabolism - taurine and hypotaurine; Other Amino Acids Metabolism - glutathione; Lipid Metabolism - arachidonic acid; Other Amino Acids Metabolism - cyanoamino acid; EC 2.3.2.2; Transferase; EC 3.4.19.13; Membrane protein, integral; Other Amino Acids Metabolism - selenoamino acidChromosomal Location of Human Ortholog: 20q11.22Cellular Component: anchored to external side of plasma membraneMolecular Function: gamma-glutamyltransferase activity; protein bindingBiological Process: glutathione metabolic process; leukotriene biosynthetic process |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UJ14 |
| NCBI GenInfo Identifier: | 152031612 |
| NCBI Gene ID: | 2686 |
| NCBI Accession: | Q9UJ14.2 |
| UniProt Secondary Accession: | Q9UJ14,Q8N899, Q8NF66, Q9BYP5, Q9BYP6 |
| UniProt Related Accession: | Q9UJ14 |
| Molecular Weight: | 15,236 Da |
| NCBI Full Name: | Gamma-glutamyltransferase 7 |
| NCBI Synonym Full Names: | gamma-glutamyltransferase 7 |
| NCBI Official Symbol: | GGT7 |
| NCBI Official Synonym Symbols: | GGT4; GGTL3; GGTL5; D20S101; dJ18C9.2 |
| NCBI Protein Information: | gamma-glutamyltransferase 7 |
| UniProt Protein Name: | Gamma-glutamyltransferase 7 |
| UniProt Synonym Protein Names: | Gamma-glutamyltransferase-like 3; Gamma-glutamyltransferase-like 5; Gamma-glutamyltranspeptidase 7; Glutathione hydrolase 7 (EC:3.4.19.13) |
| Protein Family: | Gamma-glutamyltransferase |
| UniProt Gene Name: | GGT7 |
| UniProt Entry Name: | GGT7_HUMAN |
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