Cleaved Gasdermin B（C Terminal） Monoclonal Antibody
- SKU:
- CAB24342
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Cleaved Gasdermin B（C Terminal） Monoclonal Antibody |
| Product Code: | CAB24342 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC63400 |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | GSDMB-C-6-his |
| Cellular Location: | Cytoplasm |
This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Alternative splicing and the use of alternative promoters results in multiple transcript variants. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 245-253 of human Gasdermin B (NP_001159430.1). |
| Sequence: | SLGSE DSRN- C |
| Synonyms: | GSDML, PP4052, GSDMB-1, PRO2521 |
| Calculated MW: | 18kDa/45kDa/46kDa/47kDa |
| Observed MW: | 16kDa |
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