Claudin-3 Monoclonal Antibody
- SKU:
- CAB24603
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | Claudin-3 Monoclonal Antibody |
| Product Code: | CAB24603 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC64060 |
| Reactivity: | Human |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200, IF 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HT-29 |
| Cellular Location: | Cell junction, tight junction, cell membrane |
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 121-220 of human Claudin-3 mAb (NP_001297.1). |
| Sequence: | GVLFL LAALL TLVPV SWSAN TIIRD FYNPV VPEAQ KREMG AGLYV GWAAA ALQLL GGALL CCSCP PREKK YTATK VVYSA PRSTG PGASL GTGYD RKDYV |
| Synonyms: | RVP1, HRVP1, C7orf1, CPE-R2, CPETR2 |
| Calculated MW: | 23kDa |
| Observed MW: | 20kDa |
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