Claudin 1 Polyclonal Antibody (CAB21770)
- SKU:
- CAB21770
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Claudin 1 Polyclonal Antibody |
| Product Code: | CAB21770 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | A-431 |
| Cellular Location: | Cell junction, Cell membrane, Multi-pass membrane protein, tight junction |
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 111-211 of human Claudin 1 (NP_066924.1). |
| Sequence: | DEVQK MRMAV IGGAI FLLAG LAILV ATAWY GNRIV QEFYD PMTPV NARYE FGQAL FTGWA AASLC LLGGA LLCCS CPRKT TSYPT PRPYP KPAPS SGKDY V |
| Synonyms: | CLD1, SEMP1, ILVASC |
| Calculated MW: | 23kDa |
| Observed MW: | 22kDa |
Related Products
Claudin 1 Polyclonal Antibody (CAB21949)
OverviewProduct Name:Claudin 1 Polyclonal AntibodyProduct Code:CAB21949Reactivity:Mouse, RatApplications:Western blotting
Claudin 1 Monoclonal Antibody (CAB23516)
Claudin 1 Monoclonal Antibody (CAB23516)The product page for this antibody is being prepared. If you have a question please don't hesitate to get in touch!
Claudin 1 Monoclonal Antibody (CAB21971)
OverviewProduct Name:Claudin 1 Monoclonal AntibodyProduct Code:CAB21971Reactivity:Human, Mouse, RatApplications:Western blotting,