Name: CKMT1A Monoclonal Antibody [PAT17A2AT] (CPAB0186)
SKU: CPAB0186
Availability: OutOfStock

CKMT1A Monoclonal Antibody [PAT17A2AT] (CPAB0186)

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SKU:

CPAB0186

Product Type:

Antibody

Antibody Type:

Monoclonal Antibody

Reactivity:

Human

Host Species:

Mouse

Description

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Cell Biology Antibodies 9

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Product Name:	CKMT1A Antibody
Product Sku:	CPAB0186
Size:	5μg
Host Species:	Mouse IgG2b
Immunogen:	Anti-human CKMT1A mAb, clone PAT17A2AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CKMT1A protein 4-417 amino acids purified from E. coli.
Clone:	PAT17A2AT.
Reactivity:	Human
Applications:	Western Blot, ELISA

Purification Method:	CKMT1A antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:	IgG1
Background:	CKMT1A is in charge of the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. CKMT1A is a member of the creatine kinase isoenzyme family and exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase arises in two different oligomeric forms: dimers and octamers, unlike the exclusively dimeric cytosolic creatine kinase isoenzymes. Numerous malignant cancers with poor prognosis have displayed overexpression of ubiquitous mitochondrial creatine kinase which is linked to high energy turnover and inability to remove cancer cells through apoptosis.
Synonyms:	Creatine kinase mitochondrial 1A, creatine kinase mitochondrial 1 (ubiquitous), creatine kinase U-type mitochondrial, Acidic-type mitochondrial creatine kinase, Ubiquitous mitochondrial creatine kinase, CKMT1, U-MtCK, mia-CK, EC 2.7.3, EC 2.7.3.2.
Storage Buffer:	For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.