CKMT1A Monoclonal Antibody [PAT17A2AT] (CPAB0186)
![CKMT1A Monoclonal Antibody [PAT17A2AT] (CPAB0186)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58412/63594/assay-genie-box-4__63829.1706535002.jpg?c=1 "CKMT1A Monoclonal Antibody [PAT17A2AT] (CPAB0186)")
- SKU:
- CPAB0186
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
![CKMT1A Monoclonal Antibody [PAT17A2AT] (CPAB0186)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58412/63594/assay-genie-box-4__63829.1706535002.jpg?c=1&imbypass=on "CKMT1A Monoclonal Antibody [PAT17A2AT] (CPAB0186)")
Description
system_update_alt Datasheet
| Product Name: | CKMT1A Antibody |
| Product Sku: | CPAB0186 |
| Size: | 5μg |
| Host Species: | Mouse IgG2b |
| Immunogen: | Anti-human CKMT1A mAb, clone PAT17A2AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CKMT1A protein 4-417 amino acids purified from E. coli. |
| Clone: | PAT17A2AT. |
| Reactivity: | Human |
| Applications: | Western Blot, ELISA |
| Purification Method: | CKMT1A antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
| Isotype: | IgG1 |
| Background: | CKMT1A is in charge of the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. CKMT1A is a member of the creatine kinase isoenzyme family and exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase arises in two different oligomeric forms: dimers and octamers, unlike the exclusively dimeric cytosolic creatine kinase isoenzymes. Numerous malignant cancers with poor prognosis have displayed overexpression of ubiquitous mitochondrial creatine kinase which is linked to high energy turnover and inability to remove cancer cells through apoptosis. |
| Synonyms: | Creatine kinase mitochondrial 1A, creatine kinase mitochondrial 1 (ubiquitous), creatine kinase U-type mitochondrial, Acidic-type mitochondrial creatine kinase, Ubiquitous mitochondrial creatine kinase, CKMT1, U-MtCK, mia-CK, EC 2.7.3, EC 2.7.3.2. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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