CKAP2L Antibody (PACO46766)
- SKU:
- PACO46766
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CKAP2L Antibody (PACO46766) |
| Antibody SKU: | PACO46766 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Cytoskeleton-associated protein 2-like protein (246-413AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human melanoma using PACO46766 at dilution of 1:100. |
 | Immunofluorescent analysis of HepG2 cells using PACO46766 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human brain tissue using PACO46766 at dilution of 1:100. |
| Background: | Microtubule-associated protein required for mitotic spindle formation and cell-cycle progression in neural progenitor cells. |
| Synonyms: | Cytoskeleton-associated protein 2-like (Radial fiber and mitotic spindle protein) (Radmis), CKAP2L |
| UniProt Protein Function: | CKAP2L: Belongs to the CKAP2 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 2q13Cellular Component: spindle pole; centrosome; cytoplasmDisease: Filippi Syndrome |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is thought to be a mitotic spindle protein important to neural stem or progenitor cells. Mutations in this gene have been associated with spindle organization defects, including mitotic spindle defects, lagging chromosomes, and chromatin bridges. There is evidence that mutations in this gene are associated with Filippi syndrome, characterized by growth defects, microcephaly, intellectual disability, facial feature defects, and syndactyly. There is a pseudogene of this gene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] |
| UniProt Code: | Q8IYA6 |
| NCBI GenInfo Identifier: | 748983483 |
| NCBI Gene ID: | 150468 |
| NCBI Accession: | NP_001291290.1 |
| UniProt Secondary Accession: | Q8IYA6,Q53QF8, Q53RS8, Q8N1J8, A8K915, B4DZE3, B7ZAC6 F5H0M5 |
| UniProt Related Accession: | Q8IYA6 |
| Molecular Weight: | Calculated MW: 84kDaObserved MW: 84kDa |
| NCBI Full Name: | cytoskeleton-associated protein 2-like isoform 2 |
| NCBI Synonym Full Names: | cytoskeleton associated protein 2-like |
| NCBI Official Symbol: | CKAP2L |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | cytoskeleton-associated protein 2-like; radial fiber and mitotic spindle protein; radmis |
| UniProt Protein Name: | Cytoskeleton-associated protein 2-like |
| UniProt Synonym Protein Names: | Radial fiber and mitotic spindle protein; Radmis |
| Protein Family: | Cytoskeleton-associated protein |
| UniProt Gene Name: | CKAP2L |
| UniProt Entry Name: | CKP2L_HUMAN |
| Antibodies |
| CKAP2L Antibody (PACO08443) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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