Description
Product Name: | CK14 Polyclonal Antibody |
Product Code: | CAB24481 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:1000-1:5000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | A431 |
Cellular Location: | Cytoplasm, Nucleus |
This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 372-472 of human CK14 (NP_000517.3). |
Sequence: | QIQEM IGSVE EQLAQ LRCEM EQQNQ EYKIL LDVKT RLEQE IATYR RLLEG EDAHL SSSQF SSGSQ SSRDV TSSSR QIRTK VMDVH DGKVV STHEQ VLRTK N |
Synonyms: | KRT14, CK14, EBS3, EBS4, K14, NFJ, keratin 14 |
Calculated MW: | 51kDa |
Observed MW: | Refer to figures |