cIAP1 Polyclonal Antibody
- SKU:
- CAB21458
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | cIAP1 Polyclonal Antibody |
| Product Code: | CAB21458 |
| Reactivity: | Human, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Cellular Location: | Cytoplasm, Nucleus |
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 331-420 of human cIAP1 (NP_001157.1). |
| Sequence: | PRCEF LIRMK GQEFV DEIQG RYPHL LEQLL STSDT TGEEN ADPPI IHFGP GESSS EDAVM MNTPV VKSAL EMGFN RDLVK QTVQS KILTT |
| Synonyms: | API1, MIHB, HIAP2, RNF48, cIAP1, Hiap-2, c-IAP1 |
| Calculated MW: | 70kDa |
| Observed MW: | Refer to figures |
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