CIAO2A Antibody (PACO41078)
- SKU:
- PACO41078
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CIAO2A Antibody (PACO41078) |
| Antibody SKU: | PACO41078 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Cytosolic iron-sulfur assembly component 2A protein (1-160AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: CIAO2A antibody at 8µg/ml + NIH/3T3 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 19, 12 kDa. Observed band size: 19 kDa. |
| Background: | Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation. May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 |
| Synonyms: | Cytosolic iron-sulfur assembly component 2A, MIP18 family protein FAM96A, CIAO2A, CIA2A, FAM96A |
| UniProt Protein Function: | FAM96A: May play a role in chromosome segregation through establishment of sister chromatid cohesion. Belongs to the MIP18 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 15q22.31Cellular Component: nucleoplasm; cytoplasmMolecular Function: metal ion bindingBiological Process: iron-sulfur cluster assembly; chromosome segregation |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9H5X1 |
| NCBI GenInfo Identifier: | 14149934 |
| NCBI Gene ID: | 84191 |
| NCBI Accession: | NP_115607.1 |
| UniProt Secondary Accession: | Q9H5X1,A6NKS1, B2R5F8, B7Z8Z5 |
| UniProt Related Accession: | Q9H5X1 |
| Molecular Weight: | 11,634 Da |
| NCBI Full Name: | MIP18 family protein FAM96A isoform a |
| NCBI Synonym Full Names: | family with sequence similarity 96 member A |
| NCBI Official Symbol: | FAM96A |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | MIP18 family protein FAM96A |
| UniProt Protein Name: | MIP18 family protein FAM96A |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | FAM96A |
| UniProt Entry Name: | FA96A_HUMAN |
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