CHST13 Antibody (PACO23403)
- SKU:
- PACO23403
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CHST13 Antibody (PACO23403) |
| Antibody SKU: | PACO23403 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from internal of human CHST13. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from K562 cells, using CHST13 antibody. |
 | Immunohistochemistry analysis of paraffin-embedded human testis tissue, using CHST13 antibody. |
| Background: | Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Transfers sulfate to the C4 hydroxyl of beta1,4-linked GalNAc that is substituted with a beta-linked glucuronic acid at the C-3 hydroxyl. No activity toward dermatan. |
| Synonyms: | Tumor necrosis factor receptor superfamily member 6B; Decoy receptor for Fas ligand; Decoy receptor 3; DcR3; M68 |
| UniProt Protein Function: | CHST13: Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Transfers sulfate to the C4 hydroxyl of beta1,4-linked GalNAc that is substituted with a beta-linked glucuronic acid at the C-3 hydroxyl. No activity toward dermatan. Belongs to the sulfotransferase 2 family.Protein type: EC 2.8.2.5; Membrane protein, integral; Glycan Metabolism - chondroitin sulfate biosynthesis; Transferase; Energy Metabolism - sulfurChromosomal Location of Human Ortholog: 3q21.3Cellular Component: Golgi membrane; integral to membraneMolecular Function: chondroitin 4-sulfotransferase activity; N-acetylgalactosamine 4-O-sulfotransferase activityBiological Process: carbohydrate biosynthetic process; carbohydrate metabolic process; chondroitin sulfate biosynthetic process; chondroitin sulfate metabolic process; glycosaminoglycan metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to the C4 hydroxyl of beta-1,4-linked N-acetylgalactosamine (GalNAc) flanked by glucuronic acid residue in chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. [provided by RefSeq, Aug 2011] |
| UniProt Code: | Q8NET6 |
| NCBI GenInfo Identifier: | 61211841 |
| NCBI Gene ID: | 166012 |
| NCBI Accession: | Q8NET6.1 |
| UniProt Secondary Accession: | Q8NET6,Q3SYA3, Q3SYA5 |
| UniProt Related Accession: | Q8NET6 |
| Molecular Weight: | 25,489 Da |
| NCBI Full Name: | Carbohydrate sulfotransferase 13 |
| NCBI Synonym Full Names: | carbohydrate (chondroitin 4) sulfotransferase 13 |
| NCBI Official Symbol: | CHST13 |
| NCBI Official Synonym Symbols: | C4ST3 |
| NCBI Protein Information: | carbohydrate sulfotransferase 13 |
| UniProt Protein Name: | Carbohydrate sulfotransferase 13 |
| UniProt Synonym Protein Names: | Chondroitin 4-O-sulfotransferase 3; Chondroitin 4-sulfotransferase 3; C4ST-3; C4ST3 |
| Protein Family: | Carbohydrate sulfotransferase |
| UniProt Gene Name: | CHST13 |
| UniProt Entry Name: | CHSTD_HUMAN |
| Antibodies |
| CHST13 Antibody (PACO02575) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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