CHPF Antibody (PACO23799)
- SKU:
- PACO23799
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CHPF Antibody (PACO23799) |
| Antibody SKU: | PACO23799 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from internal of human CHSS2. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from LOVO cells and K562 cells, using CHSS2 antibody. |
 | Immunofluorescence analysis of MCF-7 cells, using CHSS2 antibody. |
 | Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue using CHSS2 antibody. |
| Background: | Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Isoform 2 may facilitate PARK2 transport into the mitochondria. In collaboration with PARK2, isoform 2 may enhance cell viability and protect cells from oxidative stress. |
| Synonyms: | CHSS2; DKFZP434E0423; EC 2.4.1.175; EC 2.4.1.226; |
| UniProt Protein Function: | CHPF: a type II transmembrane protein. May act as a specific activating factor for chondroitin synthase in chondroitin biosynthesis and polymerization. Protein type: Glycan Metabolism - chondroitin sulfate biosynthesis; EC 2.4.1.226; EC 2.4.1.175; Membrane protein, integral; TransferaseChromosomal Location of Human Ortholog: 2q35Cellular Component: Golgi membraneMolecular Function: glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activityBiological Process: chondroitin sulfate biosynthetic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8IZ52 |
| NCBI GenInfo Identifier: | 311033361 |
| NCBI Gene ID: | 79586 |
| NCBI Accession: | Q8IZ52.2 |
| UniProt Secondary Accession: | Q8IZ52,Q6UXD6, Q7L4G1, Q9H0F8, Q9H618, B4DXU0 |
| UniProt Related Accession: | Q8IZ52 |
| Molecular Weight: | 68,341 Da |
| NCBI Full Name: | Chondroitin sulfate synthase 2 |
| NCBI Synonym Full Names: | chondroitin polymerizing factor |
| NCBI Official Symbol: | CHPF |
| NCBI Official Synonym Symbols: | CSS2; CHSY2 |
| NCBI Protein Information: | chondroitin sulfate synthase 2 |
| UniProt Protein Name: | Chondroitin sulfate synthase 2 |
| UniProt Synonym Protein Names: | Chondroitin glucuronyltransferase 2; Chondroitin-polymerizing factor; ChPF; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II; N-acetylgalactosaminyltransferase 2 |
| Protein Family: | Chondroitin sulfate synthase |
| UniProt Gene Name: | CHPF |
| UniProt Entry Name: | CHSS2_HUMAN |
| Antibodies | ELISA Kits |
| CHPF Antibody (PACO05365) | Human CHPF (Chondroitin sulfate synthase 2) ELISA Kit (HUFI07961) |
| CHPF Antibody (PACO08417) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
Human CHPF (Chondroitin sulfate synthase 2) ELISA Kit (HUFI07961)
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