Description
| Product Name: | CGRP Monoclonal Antibody |
| Product Code: | CAB24424 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC63672 |
| Reactivity: | Human |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:1000-1:5000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T transfected with CGRP |
| Cellular Location: | Secreted |
This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 25-125 of human CGRP (NP_001029125.1). |
| Sequence: | AAPFR SALES SPADP ATLSE DEARL LLAAL VQDYV QMKAS ELEQE QEREG SRIIA QKRAC DTATC VTHRL AGLLS RSGGV VKNNF VPTNV GSKAF GRRRR D |
| Synonyms: | CT, KC, PCT, CGRP, CALC1, CGRP1, CGRP-I, CGRP-alpha |
| Calculated MW: | 15kDa |
| Observed MW: | 14kDa |