CFHR2 Antibody (PACO33384)
- SKU:
- PACO33384
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CFHR2 Antibody (PACO33384) |
| Antibody SKU: | PACO33384 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Complement factor H-related protein 2 protein (20-269AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: CFHR2 antibody at 2µg/ml Lane 1: Hela whole cell lysate Lane 2: 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 31, 28 kDa Observed band size: 36 kDa . |
 | Immunohistochemistry of paraffin-embedded human liver tissue using PACO33384 at dilution of 1:100. |
| Background: | Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism. |
| Synonyms: | Complement factor H-related protein 2 (FHR-2) (DDESK59) (H factor-like 3) (H factor-like protein 2), CFHR2, CFHL2 FHR2 HFL3 |
| UniProt Protein Function: | CFHR2: Might be involved in complement regulation. Can associate with lipoproteins and may play a role in lipid metabolism. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 1q31.3 Cellular Component: extracellular region |
| NCBI Summary: | This gene belongs to a family of complement factor H-related genes (CFHR), which are clustered together with complement factor H gene on chromosome 1, and are involved in regulation of complement. Mutations in CFHR genes have been associated with dense deposit disease and atypical haemolytic-uraemic syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2015] |
| UniProt Code: | P36980 |
| NCBI GenInfo Identifier: | 916404479 |
| NCBI Gene ID: | 3080 |
| NCBI Accession: | NP_001299601.1 |
| UniProt Secondary Accession: | P36980,Q14310, Q5T9T1, |
| UniProt Related Accession: | P36980 |
| Molecular Weight: | |
| NCBI Full Name: | complement factor H-related protein 2 isoform 2 |
| NCBI Synonym Full Names: | complement factor H related 2 |
| NCBI Official Symbol: | CFHR2 |
| NCBI Official Synonym Symbols: | FHR2; HFL3; CFHL2 |
| NCBI Protein Information: | complement factor H-related protein 2 |
| UniProt Protein Name: | Complement factor H-related protein 2 |
| UniProt Synonym Protein Names: | DDESK59; H factor-like 3; H factor-like protein 2 |
| Protein Family: | Complement factor H-related protein |
| UniProt Gene Name: | CFHR2 |
| UniProt Entry Name: | FHR2_HUMAN |
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