CFD Monoclonal Antibody
- SKU:
- CAB21110
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | CFD Monoclonal Antibody |
| Product Code: | CAB21110 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC2997 |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | U-937, Human plasma |
| Cellular Location: | Secreted |
This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-253 of human CFD (P00746). |
| Sequence: | ILGGR EAEAH ARPYM ASVQL NGAHL CGGVL VAEQW VLSAA HCLED AADGK VQVLL GAHSL SQPEP SKRLY DVLRA VPHPD SQPDT IDHDL LLLQL SEKAT LGPAV RPLPW QRVDR DVAPG TLCDV AGWGI VNHAG RRPDS LQHVL LPVLD RATCN RRTHH DGAIT ERLMC AESNR RDSCK GDSGG PLVCG GVLEG VVTSG SRVCG NRKKP GIYTR VASYA AWIDS VLA |
| Synonyms: | DF, ADN, PFD, ADIPSIN |
| Calculated MW: | 27kDa |
| Observed MW: | 27kDa |
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