CFAP45 Antibody (PACO20080)
- SKU:
- PACO20080
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CFAP45 Antibody (PACO20080) |
| Antibody SKU: | PACO20080 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human CFAP45 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20080(CFAP45 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | CCDC19 is a 466 amino acid, protein encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1 and, considering the great number of genes, there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes Lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. |
| Synonyms: | cilia and flagella associated protein 45 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9UL16 |
| NCBI GenInfo Identifier: | 81295816 |
| NCBI Gene ID: | 25790 |
| NCBI Accession: | NP_036469.2 |
| UniProt Secondary Accession: | Q9UL16 |
| UniProt Related Accession: | Q9UL16 |
| Molecular Weight: | |
| NCBI Full Name: | cilia- and flagella-associated protein 45 |
| NCBI Synonym Full Names: | cilia and flagella associated protein 45 |
| NCBI Official Symbol: | CFAP45 |
| NCBI Official Synonym Symbols: | NESG1; CCDC19 |
| NCBI Protein Information: | cilia- and flagella-associated protein 45 |
| UniProt Protein Name: | Coiled-coil domain-containing protein 19, mitochondrial |
| UniProt Synonym Protein Names: | Nasopharyngeal epithelium-specific protein 1 |
| Protein Family: | |
| UniProt Gene Name: | CCDC19 |
| UniProt Entry Name: | CCD19_HUMAN |
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