CFAP410 Antibody (PACO25352)
- SKU:
- PACO25352
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CFAP410 Antibody (PACO25352) |
| Antibody SKU: | PACO25352 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Cilia- and flagella-associated protein 410 protein (1-200AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human gastric cancer using PACO25352 at dilution of 1:100. |
| Background: | Plays a role in cilia formation and/or maintenance (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization (PubMed:21834987). Involved in DNA damage repair (PubMed:26290490). |
| Synonyms: | Cilia- and flagella-associated protein 410 (C21orf-HUMF09G8.5) (Leucine-rich repeat-containing protein 76) (YF5/A2), CFAP410, C21orf2, LRRC76 |
| UniProt Protein Function: | C21orf2: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 21q22.3Cellular Component: cytoplasm; mitochondrion; photoreceptor connecting cilium; plasma membraneMolecular Function: protein bindingBiological Process: cytoskeleton organization and biogenesis; regulation of cell shape |
| UniProt Protein Details: | |
| NCBI Summary: | Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear gene. All isoforms contain leucine-rich repeats. Three of these isoforms are mitochondrial proteins and one of them lacks the target peptide, so is not located in mitochondrion. This gene is down-regulated in Down syndrome (DS) brain, which may represent mitochondrial dysfunction in DS patients. [provided by RefSeq, Sep 2012] |
| UniProt Code: | O43822 |
| NCBI GenInfo Identifier: | 3334131 |
| NCBI Gene ID: | 755 |
| NCBI Accession: | O43822.1 |
| UniProt Secondary Accession: | O43822,O14993, Q8N5X6, Q99837, Q99838, A8MPS9 |
| UniProt Related Accession: | O43822 |
| Molecular Weight: | 40,422 Da |
| NCBI Full Name: | Protein C21orf2 |
| NCBI Synonym Full Names: | chromosome 21 open reading frame 2 |
| NCBI Official Symbol: | C21orf2 |
| NCBI Official Synonym Symbols: | LRRC76; YF5/A2 |
| NCBI Protein Information: | nuclear encoded mitochondrial protein C21orf2; protein C21orf2 |
| UniProt Protein Name: | Protein C21orf2 |
| UniProt Synonym Protein Names: | C21orf-HUMF09G8.5; Leucine-rich repeat-containing protein 76; YF5/A2 |
| Protein Family: | Protein |
| UniProt Gene Name: | C21orf2 |
| UniProt Entry Name: | CU002_HUMAN |
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