Description
| Antibody Name: | Ces1c Antibody (PACO34470) |
| Antibody SKU: | PACO34470 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:10-1:200 |
| Species Reactivity: | Mouse, Human, Rat |
| Immunogen: | Recombinant Mouse Carboxylesterase 1C protein (19-550AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: Ces1c antibody at 2µg/ml. Lane 1: Mouse liver tissue. Lane 2: Rat liver tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 62 kDa. Observed band size: 62 kDa. |
![]() | Immunohistochemistry of paraffin-embedded human colon cancer using PACO34470 at dilution of 1:10. |
![]() | Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO34470 at dilution of 1:10. |
| Background: | Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant. |
| Synonyms: | Carboxylesterase 1C (EC 3.1.1.1) (Liver carboxylesterase N) (Lung surfactant convertase) (PES-N), Ces1c, Es1 |
| UniProt Protein Function: | Es1: Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant. Belongs to the type-B carboxylesterase/lipase family.Protein type: EC 3.1.1.1Cellular Component: endoplasmic reticulum; extracellular spaceMolecular Function: 1-oxa-2-oxocycloheptane lactonase activity; 3,4-dihydrocoumarin hydrolase activity; all-trans-retinyl-palmitate hydrolase activity; butyrolactone hydrolase activity; hydrolase activity; hydrolase activity, acting on ester bonds; lipase activity; phospholipase activity; prenylcysteine methylesterase activity; retinyl-palmitate esterase activity; sulfolactone hydrolase activity |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P23953 |
| NCBI GenInfo Identifier: | 192854 |
| NCBI Gene ID: | 13884 |
| NCBI Accession: | AAA63297.1 |
| UniProt Secondary Accession: | P23953,O54936, P11374, Q8K125, E9QQ07 |
| UniProt Related Accession: | P23953 |
| Molecular Weight: | 61,056 Da |
| NCBI Full Name: | carboxylesterase |
| NCBI Synonym Full Names: | carboxylesterase 1C |
| NCBI Official Symbol: | Ces1c |
| NCBI Official Synonym Symbols: | Ee1; Es1; Es4; EsN; Ee-1; Es-4; Es-N; PESN; Ces-N |
| NCBI Protein Information: | carboxylesterase 1C |
| UniProt Protein Name: | Carboxylesterase 1C |
| UniProt Synonym Protein Names: | Liver carboxylesterase N; Lung surfactant convertase; PES-N |
| Protein Family: | Carboxylesterase |
| UniProt Gene Name: | Ces1c |
| UniProt Entry Name: | EST1C_MOUSE |


