Description
Antibody Name: | Ces1c Antibody (PACO34470) |
Antibody SKU: | PACO34470 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:10-1:200 |
Species Reactivity: | Mouse, Human, Rat |
Immunogen: | Recombinant Mouse Carboxylesterase 1C protein (19-550AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: Ces1c antibody at 2µg/ml. Lane 1: Mouse liver tissue. Lane 2: Rat liver tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 62 kDa. Observed band size: 62 kDa. | |
Immunohistochemistry of paraffin-embedded human colon cancer using PACO34470 at dilution of 1:10. | |
Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO34470 at dilution of 1:10. |
Background: | Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant. |
Synonyms: | Carboxylesterase 1C (EC 3.1.1.1) (Liver carboxylesterase N) (Lung surfactant convertase) (PES-N), Ces1c, Es1 |
UniProt Protein Function: | Es1: Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant. Belongs to the type-B carboxylesterase/lipase family.Protein type: EC 3.1.1.1Cellular Component: endoplasmic reticulum; extracellular spaceMolecular Function: 1-oxa-2-oxocycloheptane lactonase activity; 3,4-dihydrocoumarin hydrolase activity; all-trans-retinyl-palmitate hydrolase activity; butyrolactone hydrolase activity; hydrolase activity; hydrolase activity, acting on ester bonds; lipase activity; phospholipase activity; prenylcysteine methylesterase activity; retinyl-palmitate esterase activity; sulfolactone hydrolase activity |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | P23953 |
NCBI GenInfo Identifier: | 192854 |
NCBI Gene ID: | 13884 |
NCBI Accession: | AAA63297.1 |
UniProt Secondary Accession: | P23953,O54936, P11374, Q8K125, E9QQ07 |
UniProt Related Accession: | P23953 |
Molecular Weight: | 61,056 Da |
NCBI Full Name: | carboxylesterase |
NCBI Synonym Full Names: | carboxylesterase 1C |
NCBI Official Symbol: | Ces1c |
NCBI Official Synonym Symbols: | Ee1; Es1; Es4; EsN; Ee-1; Es-4; Es-N; PESN; Ces-N |
NCBI Protein Information: | carboxylesterase 1C |
UniProt Protein Name: | Carboxylesterase 1C |
UniProt Synonym Protein Names: | Liver carboxylesterase N; Lung surfactant convertase; PES-N |
Protein Family: | Carboxylesterase |
UniProt Gene Name: | Ces1c |
UniProt Entry Name: | EST1C_MOUSE |