Description
| Antibody Name: | CERS4 Antibody (PACO23283) |
| Antibody SKU: | PACO23283 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from internal of human LASS4. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Western blot analysis of extracts from COLO cells, Jurkat cells and HUVEC cells, using LASS4 antibody. |
![]() | Immunohistochemistry analysis of paraffin-embedded human brain tissue using LASS4 antibody. |
| Background: | May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner By similarity. |
| Synonyms: | LAG1 longevity assurance homolog 4; LASS4; |
| UniProt Protein Function: | Lass4: May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner.Protein type: Membrane protein, multi-pass; Membrane protein, integral; DNA-bindingChromosomal Location of Human Ortholog: 19p13.2Cellular Component: endoplasmic reticulum; endoplasmic reticulum membraneMolecular Function: sphingosine N-acyltransferase activityBiological Process: ceramide biosynthetic process; sphingolipid biosynthetic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9HA82 |
| NCBI GenInfo Identifier: | 296434561 |
| NCBI Gene ID: | 79603 |
| NCBI Accession: | Q9HA82.2 |
| UniProt Secondary Accession: | Q9HA82,D6W665 |
| UniProt Related Accession: | Q9HA82 |
| Molecular Weight: | 46,399 Da |
| NCBI Full Name: | Ceramide synthase 4 |
| NCBI Synonym Full Names: | ceramide synthase 4 |
| NCBI Official Symbol: | CERS4 |
| NCBI Official Synonym Symbols: | Trh1; LASS4 |
| NCBI Protein Information: | ceramide synthase 4 |
| UniProt Protein Name: | Ceramide synthase 4 |
| UniProt Synonym Protein Names: | LAG1 longevity assurance homolog 4 |
| Protein Family: | Ceramide synthase |
| UniProt Gene Name: | CERS4 |
| UniProt Entry Name: | CERS4_HUMAN |
| Antibodies |
| CERS4 Antibody (PACO01014) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |

