Anti-CEP97 Antibody (PACO56006)

Name: CEP97 Antibody (PACO56006)
SKU: PACO56006
Availability: OutOfStock

Antibody Name:	CEP97 Antibody (PACO56006)
Antibody SKU:	PACO56006
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, IF
Recommended Dilutions:	ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:	Human
Immunogen:	Recombinant Human Centrosomal protein of 97 kDa protein (719-854AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Immunofluorescence staining of Hela cells with PACO56006 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Background:	Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation. Required for recruitment of CCP110 to the centrosome.
Synonyms:	Centrosomal protein of 97 kDa (Cep97) (Leucine-rich repeat and IQ domain-containing protein 2), CEP97, LRRIQ2

UniProt Protein Function:	LRRIQ2: Collaborates with CCP110, being involved in the suppression of a cilia assembly program. Required for correct spindle formation and has a role in cytokinesis. Required for recruitment of CCP110 to the centrosome. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 3q12.3Cellular Component: centrosome; protein complex; cytoplasm; microtubule organizing center; cytosolMolecular Function: calmodulin binding; protein bindingBiological Process: cell projection organization and biogenesis; organelle organization and biogenesis
UniProt Protein Details:
NCBI Summary:
UniProt Code:	Q8IW35
NCBI GenInfo Identifier:	31377705
NCBI Gene ID:	79598
NCBI Accession:	NP_078824.2
UniProt Secondary Accession:	Q8IW35,Q8NA71, Q9H5T9, B5MDY8
UniProt Related Accession:	Q8IW35
Molecular Weight:	96,981 Da
NCBI Full Name:	centrosomal protein of 97 kDa
NCBI Synonym Full Names:	centrosomal protein 97kDa
NCBI Official Symbol:	CEP97
NCBI Official Synonym Symbols:	LRRIQ2; 2810403B08Rik
NCBI Protein Information:	centrosomal protein of 97 kDa; leucine-rich repeats and IQ motif containing 2; leucine-rich repeat and IQ domain-containing protein 2
UniProt Protein Name:	Centrosomal protein of 97 kDa
UniProt Synonym Protein Names:	Leucine-rich repeat and IQ domain-containing protein 2
Protein Family:	Centrosomal protein
UniProt Gene Name:	CEP97
UniProt Entry Name:	CEP97_HUMAN