CEP97 Antibody (PACO56006)
- SKU:
- PACO56006
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CEP97 Antibody (PACO56006) |
| Antibody SKU: | PACO56006 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Centrosomal protein of 97 kDa protein (719-854AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescence staining of Hela cells with PACO56006 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation. Required for recruitment of CCP110 to the centrosome. |
| Synonyms: | Centrosomal protein of 97 kDa (Cep97) (Leucine-rich repeat and IQ domain-containing protein 2), CEP97, LRRIQ2 |
| UniProt Protein Function: | LRRIQ2: Collaborates with CCP110, being involved in the suppression of a cilia assembly program. Required for correct spindle formation and has a role in cytokinesis. Required for recruitment of CCP110 to the centrosome. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 3q12.3Cellular Component: centrosome; protein complex; cytoplasm; microtubule organizing center; cytosolMolecular Function: calmodulin binding; protein bindingBiological Process: cell projection organization and biogenesis; organelle organization and biogenesis |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8IW35 |
| NCBI GenInfo Identifier: | 31377705 |
| NCBI Gene ID: | 79598 |
| NCBI Accession: | NP_078824.2 |
| UniProt Secondary Accession: | Q8IW35,Q8NA71, Q9H5T9, B5MDY8 |
| UniProt Related Accession: | Q8IW35 |
| Molecular Weight: | 96,981 Da |
| NCBI Full Name: | centrosomal protein of 97 kDa |
| NCBI Synonym Full Names: | centrosomal protein 97kDa |
| NCBI Official Symbol: | CEP97 |
| NCBI Official Synonym Symbols: | LRRIQ2; 2810403B08Rik |
| NCBI Protein Information: | centrosomal protein of 97 kDa; leucine-rich repeats and IQ motif containing 2; leucine-rich repeat and IQ domain-containing protein 2 |
| UniProt Protein Name: | Centrosomal protein of 97 kDa |
| UniProt Synonym Protein Names: | Leucine-rich repeat and IQ domain-containing protein 2 |
| Protein Family: | Centrosomal protein |
| UniProt Gene Name: | CEP97 |
| UniProt Entry Name: | CEP97_HUMAN |
| Antibodies |
| CEP97 Antibody (PACO05366) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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