CEP97 Antibody (PACO16017)
- SKU:
- PACO16017
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CEP97 Antibody (PACO16017) |
| Antibody SKU: | PACO16017 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human CEP97 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO16017(CEP97 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
 | Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-5: 293T cells, hela cells, PC3 cells, lovo cells, A172 cells, Primary antibody: PACO16017(CEP97 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO16017(CEP97 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | Centrosomal protein of 97 kDa (Cep97), also known as leucine-rich repeat and IQ domain-containing protein 2 (LRRIQ2), is a protein that in humans is encoded by the CEP97 gene. Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation. Required for recruitment of CCP110 to the centrosome. Interacts with CALM1, CEP76 and CCP110. Via its interaction with CCP110, may indirectly interact with HERC2 and NEURL4. Interacts with KIF24. |
| Synonyms: | centrosomal protein 97kDa |
| UniProt Protein Function: | LRRIQ2: Collaborates with CCP110, being involved in the suppression of a cilia assembly program. Required for correct spindle formation and has a role in cytokinesis. Required for recruitment of CCP110 to the centrosome. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 3q12.3Cellular Component: centrosome; protein complex; cytoplasm; microtubule organizing center; cytosolMolecular Function: calmodulin binding; protein bindingBiological Process: cell projection organization and biogenesis; organelle organization and biogenesis |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8IW35 |
| NCBI GenInfo Identifier: | 31377705 |
| NCBI Gene ID: | 79598 |
| NCBI Accession: | NP_078824.2 |
| UniProt Secondary Accession: | Q8IW35,Q8NA71, Q9H5T9, B5MDY8 |
| UniProt Related Accession: | Q8IW35 |
| Molecular Weight: | 96,981 Da |
| NCBI Full Name: | centrosomal protein of 97 kDa |
| NCBI Synonym Full Names: | centrosomal protein 97kDa |
| NCBI Official Symbol: | CEP97 |
| NCBI Official Synonym Symbols: | LRRIQ2; 2810403B08Rik |
| NCBI Protein Information: | centrosomal protein of 97 kDa; leucine-rich repeats and IQ motif containing 2; leucine-rich repeat and IQ domain-containing protein 2 |
| UniProt Protein Name: | Centrosomal protein of 97 kDa |
| UniProt Synonym Protein Names: | Leucine-rich repeat and IQ domain-containing protein 2 |
| Protein Family: | Centrosomal protein |
| UniProt Gene Name: | CEP97 |
| UniProt Entry Name: | CEP97_HUMAN |
| Antibodies |
| CEP97 Antibody (PACO05366) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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