CEP72 Antibody (PACO45063)
- SKU:
- PACO45063
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CEP72 Antibody (PACO45063) |
| Antibody SKU: | PACO45063 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Centrosomal protein of 72 kDa protein (200-460AA) |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: CEP72 antibody at 3.37µg/ml + Hela whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 72, 22 kDa. Observed band size: 72 kDa.. |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO45063 at dilution of 1:100. |
| Background: | Involved in the recruitment of key centrosomal proteins to the centrosome. Provides centrosomal microtubule-nucleation activity on the gamma-tubulin ring complexes (gamma-TuRCs) and has critical roles in forming a focused bipolar spindle, which is needed for proper tension generation between sister chromatids. Required for localization of KIZ, AKAP9 and gamma-tubulin ring complexes (gamma-TuRCs). Involved in centriole duplication. Required for CDK5RAP22, CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2. |
| Synonyms: | Centrosomal protein of 72 kDa (Cep72), CEP72, KIAA1519 |
| UniProt Protein Function: | CEP72: Involved in the recruitment of key centrosomal proteins to the centrosome. Provides centrosomal microtubule-nucleation activity on the gamma-tubulin ring complexes (gamma-TuRCs) and has critical roles in forming a focused bipolar spindle, which is needed for proper tension generation between sister chromatids. Required for localization of KIZ/PLK1S1, AKAP9 and gamma-tubulin ring complexes (gamma-TuRCs). Belongs to the CEP72 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Microtubule-bindingChromosomal Location of Human Ortholog: 5p15.33Cellular Component: centrosome; cytosolMolecular Function: protein bindingBiological Process: centriole replication; G2/M transition of mitotic cell cycle; gamma-tubulin complex localization; spindle organization and biogenesis |
| UniProt Protein Details: | |
| NCBI Summary: | The product of this gene is a member of the leucine-rich-repeat (LRR) superfamily of proteins. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9P209 |
| NCBI GenInfo Identifier: | 62901504 |
| NCBI Gene ID: | 55722 |
| NCBI Accession: | Q9P209.2 |
| UniProt Secondary Accession: | Q9P209,Q9BV03, Q9BWM3, Q9NVR4, B4DR26 |
| UniProt Related Accession: | Q9P209 |
| Molecular Weight: | 21,336 Da |
| NCBI Full Name: | Centrosomal protein of 72 kDa |
| NCBI Synonym Full Names: | centrosomal protein 72 |
| NCBI Official Symbol: | CEP72 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | centrosomal protein of 72 kDa |
| UniProt Protein Name: | Centrosomal protein of 72 kDa |
| UniProt Synonym Protein Names: | |
| Protein Family: | Centrosomal protein |
| UniProt Gene Name: | CEP72 |
| UniProt Entry Name: | CEP72_HUMAN |
| Antibodies |
| CEP72 Antibody (PACO08370) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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