CENPP Antibody (PACO16004)
- SKU:
- PACO16004
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CENPP Antibody (PACO16004) |
| Antibody SKU: | PACO16004 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human CENPP |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: 293T cells, Primary antibody: PACO16004(CENPP Antibody) at dilution 1/449, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes. |
| Background: | CENPP is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression. Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. |
| Synonyms: | centromere protein P |
| UniProt Protein Function: | CENPP: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.Chromosomal Location of Human Ortholog: 9q22.31Cellular Component: nucleoplasm; cytosol; chromosome, pericentric regionBiological Process: nucleosome assembly; DNA replication-independent nucleosome assembly at centromere; mitotic cell cycle |
| UniProt Protein Details: | |
| NCBI Summary: | CENPP is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q6IPU0 |
| NCBI GenInfo Identifier: | 47939542 |
| NCBI Gene ID: | 401541 |
| NCBI Accession: | AAH71726.1 |
| UniProt Secondary Accession: | Q6IPU0,Q5T9F8, Q5T9F9, B3KRA5, B3KS17 |
| UniProt Related Accession: | Q6IPU0 |
| Molecular Weight: | 12,707 Da |
| NCBI Full Name: | Centromere protein P |
| NCBI Synonym Full Names: | centromere protein P |
| NCBI Official Symbol: | CENPP |
| NCBI Official Synonym Symbols: | CENP-P |
| NCBI Protein Information: | centromere protein P |
| UniProt Protein Name: | Centromere protein P |
| UniProt Synonym Protein Names: | |
| Protein Family: | Centromere protein |
| UniProt Gene Name: | CENPP |
| UniProt Entry Name: | CENPP_HUMAN |
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