CENPO Antibody (PACO16007)
- SKU:
- PACO16007
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CENPO Antibody (PACO16007) |
| Antibody SKU: | PACO16007 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human CENPO |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO16007(CENPO Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO16007(CENPO Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | This gene encodes a component of the interphase centromere complex. The encoded protein is localized to the centromere throughout the cell cycle and is required for bipolar spindle assembly, chromosome segregation and checkpoint signaling during mitosis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. |
| Synonyms: | centromere protein O |
| UniProt Protein Function: | CENPO: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Modulates the kinetochore-bound levels of NDC80 complex. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 2p23.3Cellular Component: cytosol; nucleoplasmMolecular Function: protein bindingBiological Process: DNA replication-independent nucleosome assembly at centromere; sister chromatid cohesion |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a component of the interphase centromere complex. The encoded protein is localized to the centromere throughout the cell cycle and is required for bipolar spindle assembly, chromosome segregation and checkpoint signaling during mitosis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] |
| UniProt Code: | Q9BU64 |
| NCBI GenInfo Identifier: | 74733185 |
| NCBI Gene ID: | 79172 |
| NCBI Accession: | Q9BU64.1 |
| UniProt Secondary Accession: | Q9BU64,Q53T55, Q96JV3, B2RDC0, D6W536 |
| UniProt Related Accession: | Q9BU64 |
| Molecular Weight: | 32,989 Da |
| NCBI Full Name: | Centromere protein O |
| NCBI Synonym Full Names: | centromere protein O |
| NCBI Official Symbol: | CENPO |
| NCBI Official Synonym Symbols: | CENP-O; MCM21R; ICEN-36 |
| NCBI Protein Information: | centromere protein O |
| UniProt Protein Name: | Centromere protein O |
| UniProt Synonym Protein Names: | Interphase centromere complex protein 36 |
| Protein Family: | Centromere protein |
| UniProt Gene Name: | CENPO |
| UniProt Entry Name: | CENPO_HUMAN |
| Antibodies |
| CENPO Antibody (PACO08366) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
SIM1 Antibody
Overview Product Name:SIM1 AntibodyProduct Code:PACO64949Size:50µLTarget Names:SIM1Species Reactivity:HumanHost
eutC Antibody
Overview Product Name:eutC AntibodyProduct Code:PACO64709Size:50µLTarget Names:eutCSpecies Reactivity:Escherichia coli
EPHA10 Antibody
Overview Product Name:EPHA10 AntibodyProduct Code:PACO64693Size:50µLTarget Names:EPHA10Species Reactivity:HumanH