CEACAM6 Monoclonal Antibody
- SKU:
- CAB22671
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | CEACAM6 Monoclonal Antibody |
| Product Code: | CAB22671 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC54333 |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | BxPC-3, A-549 |
| Cellular Location: | apical plasma membrane, cell surface, extracellular space, plasma membrane |
This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-320 of human CEACAM6 (NP_002474.4). |
| Sequence: | KLTIE STPFN VAEGK EVLLL AHNLP QNRIG YSWYK GERVD GNSLI VGYVI GTQQA TPGPA YSGRE TIYPN ASLLI QNVTQ NDTGF YTLQV IKSDL VNEEA TGQFH VYPEL PKPSI SSNNS NPVED KDAVA FTCEP EVQNT TYLWW VNGQS LPVSP RLQLS NGNMT LTLLS VKRND AGSYE CEIQN PASAN RSDPV TLNVL YGPDV PTISP SKANY RPGEN LNLSC HAASN PPAQY SWFIN GTFQQ STQEL FIPNI TVNNS GSYMC QAHNS ATGLN RTTVT MITVS G |
| Synonyms: | NCA, CEAL, CD66c |
| Calculated MW: | 37kDa |
| Observed MW: | 45-200kDa |
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Anti-CEACAM6 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0333)
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