CEACAM5 Monoclonal Antibody
- SKU:
- CAB22266
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG1, Kappa
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | CEACAM5 Monoclonal Antibody |
| Product Code: | CAB22266 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG1, Kappa |
| Clone No: | ARC56151 |
| Reactivity: | Human |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:2000-1:10000, IHC-P 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | MCF7 |
| Cellular Location: | Cell membrane, GPI-anchor, Lipid-anchor |
This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-685 of human CEACAM5 (NP_004354.3). |
| Sequence: | KLTIE STPFN VAEGK EVLLL VHNLP QHLFG YSWYK GERVD GNRQI IGYVI GTQQA TPGPA YSGRE IIYPN ASLLI QNIIQ NDTGF YTLHV IKSDL VNEEA TGQFR VYPEL PKPSI SSNNS KPVED KDAVA FTCEP ETQDA TYLWW VNNQS LPVSP RLQLS NGNRT LTLFN VTRND TASYK CETQN PVSAR RSDSV ILNVL YGPDA PTISP LNTSY RSGEN LNLSC HAASN PPAQY SWFVN GTFQQ STQEL FIPNI TVNNS GSYTC QAHNS DTGLN RTTVT TITVY AEPPK PFITS NNSNP VEDED AVALT CEPEI QNTTY LWWVN NQSLP VSPRL QLSND NRTLT LLSVT RNDVG PYECG IQNEL SVDHS DPVIL NVLYG PDDPT ISPSY TYYRP GVNLS LSCHA ASNPP AQYSW LIDGN IQQHT QELFI SNITE KNSGL YTCQA NNSAS GHSRT TVKTI TVSAE LPKPS ISSNN SKPVE DKDAV AFTCE PEAQN TTYLW WVNGQ SLPVS PRLQL SNGNR TLTLF NVTRN DARAY VCGIQ NSVSA NRSDP VTLDV LYGPD TPIIS PPDSS YLSGA NLNLS CHSAS NPSPQ YSWRI NGIPQ QHTQV LFIAK ITPNN NGTYA CFVSN LATGR NNSIV KSITV SASGT SPGLS A |
| Synonyms: | CEA, CD66e |
| Calculated MW: | 77kDa |
| Observed MW: | 200kDa |
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