CDCA7 Antibody (PACO22028)
- SKU:
- PACO22028
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CDCA7 Antibody (PACO22028) |
| Antibody SKU: | PACO22028 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from internal of human CDCA7. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from K562 cells, using CDCA7 antibody. |
| Background: | Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator. |
| Synonyms: | Cell division cycle-associated protein 7; Protein JPO1; JPO1; |
| UniProt Protein Function: | CDCA7: Participates in MYC-mediated cell transformation; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Cell cycle regulationChromosomal Location of Human Ortholog: 2q31Cellular Component: nucleoplasm; cytoplasm; nucleusBiological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; apoptosis; regulation of cell proliferation |
| UniProt Protein Details: | |
| NCBI Summary: | This gene was identified as a c-Myc responsive gene, and behaves as a direct c-Myc target gene. Overexpression of this gene is found to enhance the transformation of lymphoblastoid cells, and it complements a transformation-defective Myc Box II mutant, suggesting its involvement in c-Myc-mediated cell transformation. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9BWT1 |
| NCBI GenInfo Identifier: | 88999586 |
| NCBI Gene ID: | 83879 |
| NCBI Accession: | NP_114148.3 |
| UniProt Secondary Accession: | Q9BWT1,Q53EW5, Q580W9, Q658K4, Q658N4, Q8NBY9, Q96BV8 Q96SP5, B4DLP8, B4DV66 |
| UniProt Related Accession: | Q9BWT1 |
| Molecular Weight: | 46,400 Da |
| NCBI Full Name: | cell division cycle-associated protein 7 isoform 1 |
| NCBI Synonym Full Names: | cell division cycle associated 7 |
| NCBI Official Symbol: | CDCA7 |
| NCBI Official Synonym Symbols: | JPO1 |
| NCBI Protein Information: | cell division cycle-associated protein 7; c-Myc target JPO1; cell division cycle associated protein 7 |
| UniProt Protein Name: | Cell division cycle-associated protein 7 |
| UniProt Synonym Protein Names: | Protein JPO1 |
| Protein Family: | Cell division cycle-associated protein |
| UniProt Gene Name: | CDCA7 |
| UniProt Entry Name: | CDCA7_HUMAN |
| Antibodies |
| CDCA7 Antibody (PACO05482) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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