Description
Product Name: | CDA Monoclonal Antibody |
Product Code: | CAB24609 |
Reactivity: | Human, Mouse |
Applications: | Western blotting, Immunohistochemistry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC63545 |
Reactivity: | Human, Mouse |
Tested Applications: | WB, IHC-P, ELISA |
Key Applications: | Western blotting, Immunohistochemistry |
Recommended Dilution: | WB 1:2000-1:10000, IHC-P 1:1000-1:5000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | U-937, Mouse kidney |
Cellular Location: | Cytosol, extracellular region |
This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-146 of human CDA(NP_001776.1). |
Sequence: | MAQKR PACTL KPECV QQLLV CSQEA KKSAY CPYSH FPVGA ALLTQ EGRIF KGCNI ENACY PLGIC AERTA IQKAV SEGYK DFRAI AIASD MQDDF ISPCG ACRQV MREFG TNWPV YMTKP DGTYI VMTVQ ELLPS SFGPE DLQKT Q |
Synonyms: | CDD |
Calculated MW: | 16kDa |
Observed MW: | 16kDa |