Description
Product Name: | CD99 Polyclonal Antibody |
Product Code: | CAB24663 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Positive Samples: | MOLT-4 |
Cellular Location: | Membrane, Single-pass type I membrane protein |
The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 23-124 of human CD99(NP_002405.1). |
Sequence: | DGGFD LSDAL PDNEN KKPTA IPKKP SAGDD FDLGD AVVDG ENDDP RPPNP PKPMP NPNPN HPSSS GSFSD ADLAD GVSGG EGKGG SDGGG SHRKE GEEAD AP |
Synonyms: | MIC2, HBA71, MIC2X, MIC2Y, MSK5X |
Calculated MW: | 19kDa |
Observed MW: | 32kDa |