Description
| Product Name: | CD99 Monoclonal Antibody |
| Product Code: | CAB9791 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC1752 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, 293T, Mouse lung |
| Cellular Location: | cytoplasm, focal adhesion, plasma membrane |
The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CD99 (NP_002405.1). |
| Sequence: | MARGA ALALL LFGLL GVLVA APDGG FDLSD ALPDN ENKKP TAIPK KPSAG DDFDL GDAVV DGEND DPRPP NPPKP MPNPN PNHPS SSGSF SDADL ADGVS |
| Synonyms: | MIC2, HBA71, MIC2X, MIC2Y, MSK5X |
| Calculated MW: | 19kDa |
| Observed MW: | 28-30kDa |
