Description
system_update_alt Datasheet
| Product Name: | CD86 Antibody, FITC |
| Product Sku: | CPAB0369 |
| Size: | 500μg |
| Host Species: | Rat |
| Immunogen: | Purified mouse LPS-activated B cells. |
| Clone: | mB7-2. |
| Reactivity: | Mouse |
| Applications: |
| Purification Method: | Protein A |
| Isotype: | IgG2a |
| Background: | CD86 type I membrane protein is a member of the immunoglobulin superfamily which is expressed by antigen-presenting cells, and acts as the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. CD86 binding with CD28 protein is a co-stimulatory signal for initiation of the T-cell. CD86 binding with CTLA-4 negatively regulates T-cell activation and diminishes the immune response. |
| Synonyms: | B70, B7-2, LAB72, CD28LG2, FUN-1, BU63. |
| Storage Buffer: | Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |