CD86 Monoclonal Antibody
- SKU:
- CAB21198
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
- Applications:
- FC
Description
| Product Name: | CD86 Monoclonal Antibody |
| Product Code: | CAB21198 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunofluorescence, Flow Cytometry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC54011 |
| Reactivity: | Human |
| Tested Applications: | WB, IF/ICC, FC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence, Flow Cytometry |
| Recommended Dilution: | WB 1:10000-1:90000, IF/ICC 1:50-1:200, FC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Raji |
| Cellular Location: | Cell membrane |
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-241 of human CD86 (NP_787058.5). |
| Sequence: | LSGAA PLKIQ AYFNE TADLP CQFAN SQNQS LSELV VFWQD QENLV LNEVY LGKEK FDSVH SKYMG RTSFD SDSWT LRLHN LQIKD KGLYQ CIIHH KKPTG MIRIH QMNSE LSVLA NFSQP EIVPI SNITE NVYIN LTCSS IHGYP EPKKM SVLLR TKNST IEYDG VMQKS QDNVT ELYDV SISLS VSFPD VTSNM TIFCI LETDK TRLLS SPFSI ELEDP QP |
| Synonyms: | B70, B7-2, B7.2, LAB72, CD28LG2 |
| Calculated MW: | 38kDa |
| Observed MW: | 60-85kDa |
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