Cd82 Antibody (PACO25636)
- SKU:
- PACO25636
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Cd82 Antibody (PACO25636) |
| Antibody SKU: | PACO25636 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Mouse, Human |
| Immunogen: | Recombinant Mouse CD82 antigen protein (111-227AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: Cd82 antibody at 2µg/ml Lane 1: Jurkat whole cell lysate Lane 2: A549 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 30 kDa Observed band size: 30 kDa . |
| Background: | Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway. |
| Synonyms: | CD82 antigen (C33 antigen) (IA4) (Inducible membrane protein R2) (Metastasis suppressor Kangai-1 homolog) (CD antigen CD82), Cd82, Kai1 |
| UniProt Protein Function: | CD82: a widespread transmembrane protein of the tetraspanin family. A metastasis-suppressor whose decreased expression may be involved in malignant progression. Suppresses tumor metastasis of many cancers including cancers of the prostate, bladder, colon, cervix, liver, and lung (NSCLC). It is a target of estrogen receptor-mediated gene repression and is downregulated in primary human breast cancer. May be a prognostic marker for lung cancer and tumor metastatic potential. Interacts with cell surface proteins including integrins, cadherins, CD4, CD8, IGSF8. Modulates EGFR signaling. May suppress invasion by inhibiting integrin-dependent crosstalk with c-Met receptor and Src kinases. Its regulation of c-Met signaling apparently affects cancer cell migration.Protein type: Membrane protein, integral; Membrane protein, multi-pass; Cell surfaceCellular Component: integral to membrane; integral to plasma membrane; membraneBiological Process: cell surface receptor linked signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P40237 |
| NCBI GenInfo Identifier: | 209862915 |
| NCBI Gene ID: | 12521 |
| NCBI Accession: | NP_001129527.1 |
| UniProt Secondary Accession: | P40237 |
| UniProt Related Accession: | P40237 |
| Molecular Weight: | 29.5 kDa |
| NCBI Full Name: | CD82 antigen |
| NCBI Synonym Full Names: | CD82 antigen |
| NCBI Official Symbol: | Cd82 |
| NCBI Official Synonym Symbols: | C33; IA4; Kai1; Tspan27; AA682076; AL023070 |
| NCBI Protein Information: | CD82 antigen |
| UniProt Protein Name: | CD82 antigen |
| UniProt Synonym Protein Names: | C33 antigen; IA4; Inducible membrane protein R2; Metastasis suppressor Kangai-1 homolog; CD_antigen: CD82 |
| Protein Family: | CD82 antigen |
| UniProt Gene Name: | Cd82 |
| UniProt Entry Name: | CD82_MOUSE |
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