Description
Product Name: | CD81 Monoclonal Antibody |
Product Code: | CAB22528 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC57928 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, ELISA |
Key Applications: | Western blotting, Immunohistochemistry |
Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:100-1:500 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | Raji, Rat brain |
Cellular Location: | Membrane, Multi-pass membrane protein |
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 114-199 of human CD81 (NP_004347.1). |
Sequence: | VNKDQ IAKDV KQFYD QALQQ AVVDD DANNA KAVVK TFHET LDCCG SSTLT ALTTS VLKNN LCPSG SNIIS NLFKE DCHQK IDDLF S |
Synonyms: | S5.7, CVID6, TAPA1, TSPAN28 |
Calculated MW: | 26kDa |
Observed MW: | 20kDa |