Description
Product Name: | CD80 Monoclonal Antibody |
Product Code: | CAB23688 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Flow Cytometry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC61485 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, FC, ELISA |
Key Applications: | Western blotting, Flow Cytometry |
Recommended Dilution: | WB 1:500-1:1000, FC 1:100-1:500 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | Raji, RAW 264.7, C2C12 |
Cellular Location: | Membrane, Single-pass type I membrane protein Philippe Le Mercier |
Predicted to enable coreceptor activity. Acts upstream of or within T cell costimulation; cellular response to lipopolysaccharide; and positive regulation of alpha-beta T cell proliferation. Located in external side of plasma membrane. Is expressed in heart ventricle and skin. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human CD80 (CD80 molecule).
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 38-245 of mouse CD80(NP_033985.3) |
Sequence: | VDEQL SKSVK DKVLL PCRYN SPHED ESEDR IYWQK HDKVV LSVIA GKLKV WPEYK NRTLY DNTTY SLIIL GLVLS DRGTY SCVVQ KKERG TYEVK HLALV KLSIK ADFST PNITE SGNPS ADTKR ITCFA SGGFP KPRFS WLENG RELPG INTTI SQDPE SELYT ISSQL DFNTT RNHTI KCLIK YGDAH VSEDF TWEKP PEDPP DSK |
Synonyms: | B71, Ly53, TSA1, Cd28l, Ly-53, MIC17 |
Calculated MW: | 34kDa |
Observed MW: | 50-75kDa |