CD8 Monoclonal Antibody, Biotin [hCD8] (CPAB0300)
![CD8 Monoclonal Antibody, Biotin [hCD8] (CPAB0300)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58524/63706/cd8-monoclonal-antibody-biotin-hcd8-cpab0300__38886__03909.1706535129.jpg?c=1 "CD8 Monoclonal Antibody, Biotin [hCD8] (CPAB0300)")
- SKU:
- CPAB0300
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG2a
- Clone:
- hCD8
![CD8 Monoclonal Antibody, Biotin [hCD8] (CPAB0300)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58524/63706/cd8-monoclonal-antibody-biotin-hcd8-cpab0300__38886__03909.1706535129.jpg?c=1&imbypass=on "CD8 Monoclonal Antibody, Biotin [hCD8] (CPAB0300)")
Description
system_update_alt Datasheet
| Product Name: | CD8 Antibody, Biotin |
| Product Sku: | CPAB0300 |
| Size: | 500μg |
| Host Species: | Mouse |
| Immunogen: | Purified human PBL CD8+ T cells. |
| Clone: | hCD8. |
| Reactivity: | Human |
| Applications: |
| Purification Method: | Ion exchange column. |
| Isotype: | IgG2a |
| Background: | CD8 is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 acts as a co-receptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional CD8 is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8 identifies cytotoxic/suppressor t-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of t-cell mediated killing. CD8 alpha chains binds to class-I MHC molecules alpha-3 domains. |
| Synonyms: | CD8, MAL, p32. |
| Storage Buffer: | Lyophilized: store at 4C. After reconstitution, if not intended for use within a month, aliquot and store at -20C. |
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