CD79a monoclonal antibody (AGIM0057)

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SKU:
AGIM0057
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
HM57
Conjugation:
Unconjugated
Applications:
FC

Description

system_update_altDatasheet
Product Name:CD79a monoclonal antibody
Product Code:AGIM0057
Size:100 µg in 100 µL
Reactivity:Human, Mouse, Rat
Clone:HM57
Applications:Flow Cytometry
Conjugate:Unconjugated
Isotype:IgG1
Host Species:Mouse
Storage:Store at 4°C. For long-term storage aliquot and store at -20°C. Avoid freeze/thaw cycles.
Uniprot:P11912
UniProt Protein Function:Ig-alpha: an integral membrane protein that associates with surface immunoglobulin B lymphocyte antigen receptor multimeric complex. Surface Ig non-covalently associates with 2 other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. Two alternatively spliced isoforms have been described.
UniProt Protein Details:

Protein type:Membrane protein, integral; Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: B cell receptor complex; cytoplasm; external side of plasma membrane; integral to plasma membrane; lipid raft; multivesicular body; plasma membrane

Molecular Function:protein binding

Biological Process: B cell activation; B cell differentiation; B cell proliferation; B cell receptor signaling pathway

Disease: Agammaglobulinemia 3, Autosomal Recessive

NCBI Summary:The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
UniProt Code:P11912
NCBI GenInfo Identifier:547896
NCBI Gene ID:973
NCBI Accession:P11912.2
UniProt Secondary Accession:P11912,Q53FB8, A0N775,
UniProt Related Accession:P11912
Molecular Weight:20,786 Da
NCBI Full Name:B-cell antigen receptor complex-associated protein alpha chain
NCBI Synonym Full Names:CD79a molecule
NCBI Official Symbol:CD79A  
NCBI Official Synonym Symbols:IGA; MB-1  
NCBI Protein Information:B-cell antigen receptor complex-associated protein alpha chain
UniProt Protein Name:B-cell antigen receptor complex-associated protein alpha chain
UniProt Synonym Protein Names:Ig-alpha; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein; CD_antigen: CD79a
Protein Family:B-cell antigen receptor complex-associated protein
UniProt Gene Name:CD79A  
UniProt Entry Name:CD79A_HUMAN
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