Description
system_update_altDatasheet
| Product Name: | CD79a monoclonal antibody |
| Product Code: | AGIM0057 |
| Size: | 100 µg in 100 µL |
| Reactivity: | Human, Mouse, Rat |
| Clone: | HM57 |
| Applications: | Flow Cytometry |
| Conjugate: | Unconjugated |
| Isotype: | IgG1 |
| Host Species: | Mouse |
| Storage: | Store at 4°C. For long-term storage aliquot and store at -20°C. Avoid freeze/thaw cycles. |
| Uniprot: | P11912 |
| UniProt Protein Function: | Ig-alpha: an integral membrane protein that associates with surface immunoglobulin B lymphocyte antigen receptor multimeric complex. Surface Ig non-covalently associates with 2 other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. Two alternatively spliced isoforms have been described. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Immunoglobulin superfamily Chromosomal Location of Human Ortholog: 19q13.2 Cellular Component: B cell receptor complex; cytoplasm; external side of plasma membrane; integral to plasma membrane; lipid raft; multivesicular body; plasma membrane Molecular Function:protein binding Biological Process: B cell activation; B cell differentiation; B cell proliferation; B cell receptor signaling pathway Disease: Agammaglobulinemia 3, Autosomal Recessive |
| NCBI Summary: | The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P11912 |
| NCBI GenInfo Identifier: | 547896 |
| NCBI Gene ID: | 973 |
| NCBI Accession: | P11912.2 |
| UniProt Secondary Accession: | P11912,Q53FB8, A0N775, |
| UniProt Related Accession: | P11912 |
| Molecular Weight: | 20,786 Da |
| NCBI Full Name: | B-cell antigen receptor complex-associated protein alpha chain |
| NCBI Synonym Full Names: | CD79a molecule |
| NCBI Official Symbol: | CD79AÂ Â |
| NCBI Official Synonym Symbols: | IGA; MB-1Â Â |
| NCBI Protein Information: | B-cell antigen receptor complex-associated protein alpha chain |
| UniProt Protein Name: | B-cell antigen receptor complex-associated protein alpha chain |
| UniProt Synonym Protein Names: | Ig-alpha; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein; CD_antigen: CD79a |
| Protein Family: | B-cell antigen receptor complex-associated protein |
| UniProt Gene Name: | CD79AÂ Â |
| UniProt Entry Name: | CD79A_HUMAN |
